TP53I11

Across TCGA cell cohorts, TP53I11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,274 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TP53I11-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Macroautophagy, and Regulation of protein localization to cell periphery. Each is linked with TP53I11 in more than 10 cancer types. Because this analysis shows association rather than direction, both TP53I11-to-partner and partner-to-TP53I11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by TP53I11-low versus TP53I11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53I11→partner) and Y-score (partner→TP53I11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+2.280	.001	<.001	3	10
BREAST	Macroautophagy →	+0.048	+2.363	<.001	.001	3	10
BONE	Regulation of protein localization to cell periphery →	+0.084	+2.301	<.001	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to plasma membrane →	+0.067	+1.874	.006	<.001	2	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of stem cell population maintenance →	+0.064	+2.188	.003	.001	3	9
LUNG_NSCLC_LUSC	Regulation of protein localization to plasma membrane →	+0.103	+2.308	.009	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,274 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by TP53I11 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →