TP53AIP1

Across TCGA pan-cancer cohorts, TP53AIP1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TP53AIP1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher TP53AIP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TP53AIP1 expression acts as an unfavorable survival marker.

READ, SKCM, and LUSC are the cancer types where TP53AIP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	III,IV	0.289	0.932	<.001	15	view →
SKCM	DFS	Median	All	0.241	0.624	.001	15	view →
LUSC	DFS	Median	II,III,IV	0.135	0.663	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TP53AIP1–READ (OS)

Open the READ breakdown →