TP53AIP1

Across TCGA cell cohorts, TP53AIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,738 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TP53AIP1-associated GO terms across cancer lineages are Negative regulation of mRNA catabolic process, Actin filament-based transport, and Regulation of pattern recognition receptor signaling pathway. Each is linked with TP53AIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TP53AIP1-to-partner and partner-to-TP53AIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA catabolic process grouped by TP53AIP1-low versus TP53AIP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53AIP1→partner) and Y-score (partner→TP53AIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mRNA catabolic process →	+0.050	+0.124	<.001	<.001	3	7
STOMACH	Actin filament-based transport →	+0.138	+0.361	<.001	<.001	3	6
BLOOD_Lymphoma	Regulation of pattern recognition receptor signaling pathway →	+0.024	+0.029	.009	.007	2	7
SOFT_TISSUE	Negative regulation of RNA catabolic process →	+0.075	+0.277	<.001	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Cellular response to steroid hormone stimulus →	+0.062	+1.086	<.001	.001	3	6
STOMACH	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.130	+0.411	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,738 associations by consensus.

Negative regulation of mRNA catabolic process by TP53AIP1 expression — OVARY

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