TOX3

Across TCGA patient cohorts, TOX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,954 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TOX3-associated proteins across cancer lineages are ARFGEF3, ARFGEF3_S1991, and DDAH1. Each is linked with TOX3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TOX3-to-partner and partner-to-TOX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOX3 versus ARFGEF3 in BRCA, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TOX3→partner) and Y-score (partner→TOX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFGEF3 →	+0.607	+1.249	<.001	<.001	3	7
UCEC	ARFGEF3_S1991 →	+0.753	+1.363	<.001	<.001	3	6
HNSC	DDAH1 →	+0.535	+0.634	<.001	<.001	3	6
LSCC	JUNB →	-0.477	-0.772	<.001	<.001	3	6
BRCA	ARFGEF3_S2081 →	+0.813	+1.189	<.001	<.001	3	5
CCRCC	ATP9A →	+0.431	+0.555	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,954 associations by consensus.

TOX3 vs ARFGEF3 — BRCA

Explore this scatter interactively →