TOX2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TOX2 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,931 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TOX2-associated proteins across cancer lineages are CCBE1, CD247, and CD69. Each is linked with TOX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TOX2-to-partner and partner-to-TOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOX2 versus CCBE1 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TOX2→partner) and Y-score (partner→TOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCCBE1 →+0.952+0.637<.001.00132
LUADCD247 →+0.462+0.604<.001<.00132
LSCCCD69 →+0.782+0.674<.001<.00132
LSCCCEP128_S1008 →+0.821+0.748<.001<.00132
LUADCNTRL →+0.189+0.367<.001<.00132
LUADFNBP1 →+0.370+0.583<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,931 associations by consensus.

TOX2 vs CCBE1 — LSCC

Per-sample scatter of TOX2 vs CCBE1 in LSCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration