Across TCGA pan-cancer cohorts, TOR3A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TOR3A data layer compared with 23 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TOR3A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TOR3A expression acts as an unfavorable survival marker.

BRCA, UCEC, and COAD are the cancer types where TOR3A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.603	0.924	<.001	34	view →
UCEC	OS	Median	III,IV	0.061	0.588	.018	12	view →
COAD	OS	Median	All	0.500	0.873	.014	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TOR3A tumor-vs-normal RNA expression · all TOR3A data types