TOR3A

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TOR3A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TOR3A data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TOR3A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TOR3A expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

PDAC, CCRCC, and LUAD are the cancer types where TOR3A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSQuartileAll0.5980.908.0049view →
CCRCCDFSMedianIII,IV1.0000.451.0326view →
LUADDFSTertileII,III,IV0.9900.803.0414view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration