Across TCGA patient cohorts, TOR3A mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOR3A-associated genes across cancer lineages are p62 Lck ligand and PRDX1. Each is linked with TOR3A in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR3A-to-partner and partner-to-TOR3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR3A→partner) and Y-score (partner→TOR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.641	+3.169	<.001	.020	1	1
UCEC	PRDX1 →	+0.377	+3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

TOR3A survival (RNA) · tumor vs normal (RNA) · all TOR3A data types