Across TCGA cell cohorts, TOR3A mutation is significantly associated with the mutation status of many other genes, with 826 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TOR3A-associated genes across cancer lineages are TANGO6, MCM3, and SFPQ. Each is linked with TOR3A in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR3A-to-partner and partner-to-TOR3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR3A→partner) and Y-score (partner→TOR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TANGO6 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	MCM3 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	SFPQ →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	MFN2 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	FANCD2 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	YY1AP1 →	+4.014	+4.969	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

Exploration

TOR3A survival (RNA) · tumor vs normal (RNA) · all TOR3A data types