TOR1B

Across TCGA patient cohorts, TOR1B mutation is significantly associated with the RNA expression of many other genes, with 2,635 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOR1B-associated genes across cancer lineages are RNA5SP419, SLCO1B3-SLCO1B7, and SNRPGP12. Each is linked with TOR1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR1B-to-partner and partner-to-TOR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by TOR1B-low versus TOR1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR1B→partner) and Y-score (partner→TOR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.701	+2.424	<.001	.001	3	2
UCEC	SLCO1B3-SLCO1B7 →	+0.079	+2.304	.002	.001	3	2
HNSC	SNRPGP12 →	+0.170	+5.435	.003	.005	3	2
COAD	RN7SKP65 →	+0.108	+4.666	.008	.005	3	2
UCEC	CCL5 →	+1.014	+3.601	.006	.001	3	1
UCEC	CWC25 →	+0.549	+3.753	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,635 associations by consensus.

RNA5SP419 by TOR1B expression — UCEC

Explore this box plot interactively →