TOR1AIP2

Across TCGA cell cohorts, TOR1AIP2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TOR1AIP2-associated genes across cancer lineages are C5orf52, PIK3C2G, and PNLIP. Each is linked with TOR1AIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR1AIP2-to-partner and partner-to-TOR1AIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C5orf52 grouped by TOR1AIP2-low versus TOR1AIP2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR1AIP2→partner) and Y-score (partner→TOR1AIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C5orf52 →	+0.041	+5.415	<.001	.004	3	1
BLOOD_Leukemia	PIK3C2G →	+0.025	+4.152	<.001	.009	3	1
BLOOD_Leukemia	PNLIP →	+0.026	+4.539	<.001	.007	3	1
BLOOD_Leukemia	FAM24A →	+0.064	+4.969	<.001	.003	3	1
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

C5orf52 by TOR1AIP2 expression — SKIN

Explore this box plot interactively →