TOR1AIP1

Across TCGA pan-cancer cohorts, TOR1AIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TOR1AIP1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TOR1AIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TOR1AIP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

HNSC, UCEC, and LSCC are the cancer types where TOR1AIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.623	1.000	.003	22	view →
UCEC	DFS	Quartile	II,III,IV	0.251	1.000	.003	14	view →
LSCC	DFS	Quartile	All	0.558	0.850	.012	9	view →
LUAD	OS	Median	II,III,IV	0.911	0.434	.010	7	view →
CCRCC	DFS	Quartile	II,III,IV	1.000	0.739	.014	4	view →
PDAC	OS	Median	IV	0.937	0.395	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TOR1AIP1–HNSC (DFS)

Open the HNSC breakdown →