TOR1AIP1

Across TCGA cell cohorts, TOR1AIP1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TOR1AIP1-associated genes across cancer lineages are OR4D2, OR2L8, and PPIAL4F. Each is linked with TOR1AIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR1AIP1-to-partner and partner-to-TOR1AIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D2 grouped by TOR1AIP1-low versus TOR1AIP1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR1AIP1→partner) and Y-score (partner→TOR1AIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR4D2 →	+0.012	+4.772	<.001	.002	3	1
CNS	OR2L8 →	+0.019	+4.169	<.001	.008	3	1
CNS	PPIAL4F →	+0.109	+3.832	<.001	.005	3	1
CNS	KCNK16 →	+0.096	+4.566	<.001	.001	3	1
BREAST	CDRT15L2 →	+0.010	+4.781	<.001	.003	3	1
BREAST	OR4C45 →	+0.017	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

OR4D2 by TOR1AIP1 expression — CNS

Explore this box plot interactively →