TOR1A

Across TCGA pan-cancer cohorts, TOR1A mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TOR1A data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TOR1A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TOR1A expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, PDAC, and LUAD are the cancer types where TOR1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.872	1.000	.012	30	view →
PDAC	OS	Quartile	II,III,IV	0.573	0.994	.009	23	view →
LUAD	DFS	Median	II,III,IV	0.713	0.320	.005	19	view →
LSCC	DFS	Median	All	0.892	1.000	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TOR1A–COAD (DFS)

Open the COAD breakdown →