Across TCGA patient cohorts, TOMM7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TOMM7-associated genes across cancer lineages are VNN2, FAT4, and ITGA8. Each is linked with TOMM7 in more than 3 cancer types. Because this analysis shows association rather than direction, both TOMM7-to-partner and partner-to-TOMM7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM7→partner) and Y-score (partner→TOMM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VNN2 →	-1.225	-0.721	<.001	<.001	3	4
CCRCC	FAT4 →	-0.761	-0.565	<.001	<.001	3	4
LUAD	ITGA8 →	-0.849	-0.420	<.001	<.001	3	4
CCRCC	SHE →	-0.731	-0.382	<.001	.001	3	4
BRCA	PECAM1 →	-0.545	-0.457	.003	.003	3	4
COAD	MCEMP1 →	-0.592	-0.496	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,146 associations by consensus.

Exploration

TOMM7 survival (RNA) · tumor vs normal (RNA) · all TOMM7 data types