Across TCGA pan-cancer cohorts, TOMM22P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TOMM22P3’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TOMM22P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TOMM22P3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

THCA and KIRC are the cancer types where TOMM22P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TOMM22P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	+0.016	.025	2	view →
KIRC	All	All	−0.008	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TOMM22P3 RNA expression & survival · all TOMM22P3 data types