TOM1L1

Across TCGA patient cohorts, TOM1L1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,016 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TOM1L1-associated genes across cancer lineages are CCN4, PPP1R18, and LY96. Each is linked with TOM1L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TOM1L1-to-partner and partner-to-TOM1L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOM1L1 versus CCN4 in COAD, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOM1L1→partner) and Y-score (partner→TOM1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCN4 →	-0.905	-0.333	.001	.002	3	7
BRCA	PPP1R18 →	-0.641	-0.645	<.001	<.001	3	7
COAD	LY96 →	-0.895	-0.323	<.001	<.001	3	7
COAD	AQP9 →	-1.185	-0.341	.001	<.001	3	6
UCEC	GNB4 →	-0.701	-0.615	<.001	<.001	3	6
UCEC	ADGRE2 →	-0.947	-0.722	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,016 associations by consensus.

TOM1L1 vs CCN4 — COAD

Explore this scatter interactively →