TOM1L1

Across TCGA cell cohorts, TOM1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,796 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TOM1L1-associated GO terms across cancer lineages are Blood coagulation, fibrin clot formation, Positive regulation of protein autophosphorylation, and Protein activation cascade. Each is linked with TOM1L1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TOM1L1-to-partner and partner-to-TOM1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, fibrin clot formation grouped by TOM1L1-low versus TOM1L1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOM1L1→partner) and Y-score (partner→TOM1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Blood coagulation, fibrin clot formation →	-0.315	-1.176	<.001	<.001	3	11
STOMACH	Positive regulation of protein autophosphorylation →	+0.329	+1.358	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein activation cascade →	-0.285	-0.818	.008	.002	3	10
BONE	Regulation of epithelial to mesenchymal transition →	-0.130	-1.918	.007	.004	3	9
BREAST	Positive regulation of hematopoietic stem cell proliferation →	+0.121	+1.361	<.001	<.001	3	8
BLOOD_Leukemia	Sulfur amino acid biosynthetic process →	+0.095	+1.317	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,796 associations by consensus.

Blood coagulation, fibrin clot formation by TOM1L1 expression — LIVER

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