Across TCGA patient cohorts, TOGARAM2 mutation is significantly associated with the RNA expression of many other genes, with 4,049 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOGARAM2-associated genes across cancer lineages are BUB3, CTLA4, and MAP6. Each is linked with TOGARAM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TOGARAM2-to-partner and partner-to-TOGARAM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOGARAM2→partner) and Y-score (partner→TOGARAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BUB3 →	+0.436	+3.162	<.001	<.001	3	3
UCEC	CTLA4 →	+0.663	+2.265	<.001	<.001	3	3
UCEC	MAP6 →	-0.588	-2.161	.004	.003	3	3
COAD	TIPIN →	+0.591	+3.013	<.001	<.001	3	3
UCEC	PTP4A3 →	-0.918	-1.947	<.001	<.001	3	3
COAD	CDCA2 →	+0.841	+2.598	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,049 associations by consensus.

Exploration

TOGARAM2 survival (RNA) · tumor vs normal (RNA) · all TOGARAM2 data types