Across TCGA cell cohorts, TOGARAM2 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TOGARAM2-associated genes across cancer lineages are KRTAP9-3, HTN3, and METTL4. Each is linked with TOGARAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOGARAM2-to-partner and partner-to-TOGARAM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOGARAM2→partner) and Y-score (partner→TOGARAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRTAP9-3 →	+0.033	+4.807	<.001	.006	3	1
SKIN	HTN3 →	+1.578	+3.758	<.001	.004	3	1
LARGE_INTESTINE	METTL4 →	+0.700	+3.067	.001	.009	3	1
LARGE_INTESTINE	TPO →	+0.334	+3.067	<.001	.009	3	1
LARGE_INTESTINE	KCNJ5 →	+0.729	+3.485	<.001	.002	3	1
LARGE_INTESTINE	RTCA →	+0.581	+3.215	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

TOGARAM2 survival (RNA) · tumor vs normal (RNA) · all TOGARAM2 data types