TOGARAM1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TOGARAM1 mutation is significantly associated with the RNA expression of many other genes, with 5,753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOGARAM1-associated genes across cancer lineages are FN3KRP, FKBP3, and VTI1B. Each is linked with TOGARAM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TOGARAM1-to-partner and partner-to-TOGARAM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOGARAM1→partner) and Y-score (partner→TOGARAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADFN3KRP →+0.655+3.601<.001.00134
UCECFKBP3 →+0.457+3.010<.001<.00134
UCECVTI1B →+0.349+1.884<.001<.00134
COADICMT →+0.315+2.807.009.00334
UCECMCAT →+0.270+1.820.001<.00134
UCECPOLE2 →+0.484+1.638<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,753 associations by consensus.

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