Across TCGA patient cohorts, TOGARAM1 mutation is significantly associated with the total protein of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOGARAM1-associated genes across cancer lineages are 4E-BP1, FASN, and eIF4E. Each is linked with TOGARAM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TOGARAM1-to-partner and partner-to-TOGARAM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOGARAM1→partner) and Y-score (partner→TOGARAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.283	+2.736	<.001	<.001	3	4
STAD	FASN →	+0.426	+2.185	.018	.032	3	3
UCEC	eIF4E →	+0.191	+1.509	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+1.555	+3.593	<.001	.001	3	3
STAD	Rb_pS807_S811 →	-0.461	-3.169	.023	.018	3	2
BLCA	Lck →	-0.241	-2.321	.043	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

TOGARAM1 survival (RNA) · tumor vs normal (RNA) · all TOGARAM1 data types