Across TCGA patient cohorts, TOB2 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,690 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TOB2-associated proteins across cancer lineages are ZNF787, ACTN1_S362, and CCNL1_S65. Each is linked with TOB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TOB2-to-partner and partner-to-TOB2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TOB2→partner) and Y-score (partner→TOB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZNF787 →	-0.368	-0.540	.001	<.001	3	2
UCEC	ACTN1_S362 →	+0.638	+0.578	.001	<.001	3	2
UCEC	CCNL1_S65 →	+0.472	+0.424	.003	<.001	3	2
LUAD	DMAC1 →	+0.937	+0.311	.003	.001	3	2
CCRCC	NAA30_S53 →	-1.388	-0.609	<.001	<.001	3	2
UCEC	NUBP1 →	-0.339	-0.551	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,690 associations by consensus.

Exploration

TOB2 survival (RNA) · tumor vs normal (RNA) · all TOB2 data types