Across TCGA cell cohorts, TOB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,397 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TOB2-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of cell fate commitment, and Positive regulation of T-helper 17 cell lineage commitment. Each is linked with TOB2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TOB2-to-partner and partner-to-TOB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TOB2→partner) and Y-score (partner→TOB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.176	+0.964	<.001	.003	3	15
SOFT_TISSUE	Positive regulation of cell fate commitment →	+0.200	+0.996	<.001	<.001	3	14
OVARY	Positive regulation of T-helper 17 cell lineage commitment →	+0.211	+1.005	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleotide-excision repair →	+0.084	+0.765	.002	.004	3	11
SOFT_TISSUE	Negative regulation of protein oligomerization →	+0.226	+1.102	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.103	+1.141	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,397 associations by consensus.

Exploration

TOB2 survival (RNA) · tumor vs normal (RNA) · all TOB2 data types