TOB1

Across TCGA cell cohorts, TOB1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,759 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TOB1-associated genes across cancer lineages are ZBTB7B, ZNF652, and ZFP36. Each is linked with TOB1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TOB1-to-partner and partner-to-TOB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOB1 versus ZBTB7B in BREAST, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOB1→partner) and Y-score (partner→TOB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ZBTB7B →	+1.180	+1.697	<.001	<.001	3	11
BREAST	ZNF652 →	+1.177	+1.964	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	ZFP36 →	+2.221	+1.011	<.001	<.001	2	11
BREAST	TTC39A →	+3.272	+2.279	<.001	<.001	3	8
BONE	ZFP36L2 →	+1.515	+1.085	.003	.003	2	9
STOMACH	PRR15 →	+3.109	+1.502	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,759 associations by consensus.

TOB1 vs ZBTB7B — BREAST

Explore this scatter interactively →