TNXB

Across TCGA cell cohorts, TNXB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,751 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNXB-associated GO terms across cancer lineages are Regulation of macroautophagy, Macroautophagy, and Cellular response to epidermal growth factor stimulus. Each is linked with TNXB in more than 11 cancer types. Because this analysis shows association rather than direction, both TNXB-to-partner and partner-to-TNXB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by TNXB-low versus TNXB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNXB→partner) and Y-score (partner→TNXB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.080	+0.861	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.073	+0.753	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cellular response to epidermal growth factor stimulus →	+0.121	+0.798	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.074	+0.896	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.074	+0.896	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.098	+1.067	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

Regulation of macroautophagy by TNXB expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →