TNS4

Across TCGA pan-cancer cohorts, TNS4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TNS4 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TNS4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TNS4 expression acts as an unfavorable survival marker.

LUAD, PDAC, and LSCC are the cancer types where TNS4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.246	0.925	.004	15	view →
PDAC	DFS	Median	III,IV	0.486	0.863	.020	7	view →
LSCC	DFS	Median	All	0.728	0.864	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TNS4–LUAD (OS)

Open the LUAD breakdown →