TNS4

Across TCGA cell cohorts, TNS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,762 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible TNS4-associated GO terms across cancer lineages are Positive regulation of iron ion transport, Positive regulation of iron ion transmembrane transport, and Release of cytochrome c from mitochondria. Each is linked with TNS4 in more than 9 cancer types. Because this analysis shows association rather than direction, both TNS4-to-partner and partner-to-TNS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of iron ion transport grouped by TNS4-low versus TNS4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNS4→partner) and Y-score (partner→TNS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of iron ion transport →	+1.533	+2.087	<.001	.004	3	10
OVARY	Positive regulation of iron ion transmembrane transport →	+1.533	+2.087	<.001	.004	3	10
OESOPHAGUS	Release of cytochrome c from mitochondria →	+0.122	+2.503	.008	.004	3	9
OVARY	Response to ketone →	+0.074	+1.704	<.001	<.001	3	9
STOMACH	Nail development →	+0.466	+3.366	<.001	<.001	3	9
STOMACH	Establishment or maintenance of transmembrane electrochemical gradient →	+0.272	+3.657	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,762 associations by consensus.

Positive regulation of iron ion transport by TNS4 expression — OVARY

Explore this box plot interactively →