TNS4

Across TCGA cell cohorts, TNS4 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNS4-associated genes across cancer lineages are USP17L4, KRTAP17-1, and CCL7. Each is linked with TNS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNS4-to-partner and partner-to-TNS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L4 grouped by TNS4-low versus TNS4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNS4→partner) and Y-score (partner→TNS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	USP17L4 →	+0.026	+3.082	<.001	.005	3	2
URINARY_TRACT	KRTAP17-1 →	+0.026	+5.087	<.001	.004	3	1
LUNG_SCLC	CCL7 →	+0.263	+3.459	<.001	.003	3	1
LUNG_SCLC	NLRP10 →	+0.028	+3.078	<.001	.008	3	1
SKIN	C4BPA →	+0.022	+2.791	<.001	.005	3	1
SKIN	OR2B2 →	+0.020	+3.099	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

USP17L4 by TNS4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →