TNRC6C

Across TCGA cell cohorts, TNRC6C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,091 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNRC6C-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Heterochromatin organization, and Heterochromatin formation. Each is linked with TNRC6C in more than 19 cancer types. Because this analysis shows association rather than direction, both TNRC6C-to-partner and partner-to-TNRC6C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by TNRC6C-low versus TNRC6C-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNRC6C→partner) and Y-score (partner→TNRC6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Epigenetic regulation of gene expression →	+0.072	+0.910	.001	.006	3	20
STOMACH	Heterochromatin organization →	+0.079	+1.002	.001	<.001	3	18
BONE	Heterochromatin formation →	+0.082	+1.053	<.001	<.001	3	17
BONE	Negative regulation of gene expression, epigenetic →	+0.086	+1.136	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.107	+1.397	.001	.001	3	16
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.063	+1.412	.003	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,091 associations by consensus.

Epigenetic regulation of gene expression by TNRC6C expression — STOMACH

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