TNP2

Across TCGA patient cohorts, TNP2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TNP2-associated genes across cancer lineages are Tregs, Neutrophils, and CD8+ naive T-cells. Each is linked with TNP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNP2-to-partner and partner-to-TNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tregs grouped by TNP2-low versus TNP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNP2→partner) and Y-score (partner→TNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Tregs →	+0.014	+2.979	.001	.012	3	1
UCEC	Neutrophils →	+0.016	+2.581	.009	.023	3	1
SKCM	CD8+ naive T-cells →	-0.034	-2.980	.047	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Tregs by TNP2 expression — SKCM

Explore this box plot interactively →