TNP2

Across TCGA cell cohorts, TNP2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TNP2-associated genes across cancer lineages are OR14A16, TARM1, and SCGB1C2. Each is linked with TNP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNP2-to-partner and partner-to-TNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR14A16 grouped by TNP2-low versus TNP2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNP2→partner) and Y-score (partner→TNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR14A16 →	+0.032	+5.321	<.001	.005	3	1
CNS	TARM1 →	+0.029	+5.321	<.001	.005	3	1
CNS	SCGB1C2 →	+0.263	+6.357	<.001	<.001	3	1
BLOOD_Leukemia	OR5P3 →	+0.108	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AADACL4 →	+0.026	+4.922	<.001	.009	3	1
BLOOD_Lymphoma	ADCY8 →	+0.092	+4.192	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR14A16 by TNP2 expression — CNS

Explore this box plot interactively →