TNNT3

Across TCGA cell cohorts, TNNT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,902 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNT3-associated GO terms across cancer lineages are Notch signaling pathway, Negative regulation of RNA catabolic process, and Mesenchymal cell development. Each is linked with TNNT3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TNNT3-to-partner and partner-to-TNNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch signaling pathway grouped by TNNT3-low versus TNNT3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT3→partner) and Y-score (partner→TNNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Notch signaling pathway →	+0.122	+3.773	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of RNA catabolic process →	+0.056	+2.063	<.001	<.001	3	6
BLOOD_Leukemia	Mesenchymal cell development →	+0.903	+0.892	<.001	<.001	3	5
SOFT_TISSUE	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.113	+2.462	<.001	<.001	3	5
SOFT_TISSUE	Dipeptide transmembrane transport →	-0.190	-1.303	.003	.006	3	5
SOFT_TISSUE	Dipeptide transport →	-0.190	-1.303	.003	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,902 associations by consensus.

Notch signaling pathway by TNNT3 expression — URINARY_TRACT

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