TNNT3

Across TCGA cell cohorts, TNNT3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible TNNT3-associated genes across cancer lineages are PIP and CD300H. Each is linked with TNNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNT3-to-partner and partner-to-TNNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIP grouped by TNNT3-low versus TNNT3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNT3→partner) and Y-score (partner→TNNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PIP →	+0.040	+4.807	<.001	.006	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PIP by TNNT3 expression — BLOOD_Myeloma

Explore this box plot interactively →