TNNI3K

Across TCGA patient cohorts, TNNI3K RNA expression is significantly associated with the protein abundance of many other proteins, with 10,659 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TNNI3K-associated proteins across cancer lineages are LMNB2, LTBP4, and AP4B1. Each is linked with TNNI3K in more than 3 cancer types. Because this analysis shows association rather than direction, both TNNI3K-to-partner and partner-to-TNNI3K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNI3K versus LMNB2 in PDAC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI3K→partner) and Y-score (partner→TNNI3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LMNB2 →	+0.336	+0.134	<.001	.001	3	4
PDAC	LTBP4 →	+0.568	+0.116	<.001	.001	3	4
PDAC	AP4B1 →	-0.271	-0.078	.007	.006	3	4
GBM	MLKL →	-0.549	-0.235	<.001	<.001	3	4
GBM	ARHGAP27 →	-0.419	-0.216	<.001	.003	3	4
BRCA	PARP12 →	-0.332	-0.076	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,659 associations by consensus.

TNNI3K vs LMNB2 — PDAC

Explore this scatter interactively →