TNNI2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNNI2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,283 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNNI2-associated genes across cancer lineages are CTSG, LINC01234, and TNNC1. Each is linked with TNNI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNI2-to-partner and partner-to-TNNI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNI2 versus CTSG in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI2→partner) and Y-score (partner→TNNI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCTSG →+0.925+0.926<.001<.00132
OVLINC01234 →-0.533-1.673.002<.00132
HNSCTNNC1 →+2.646+1.511<.001<.00132
HNSCANKRD1 →+2.386+1.638<.001<.00132
HNSCKLHL30 →+0.859+1.522<.001<.00132
LUADREEP1 →+0.697+0.517.005.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,283 associations by consensus.

TNNI2 vs CTSG — HNSC

Per-sample scatter of TNNI2 vs CTSG in HNSC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration