TNNI2

Across TCGA cell cohorts, TNNI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,583 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNI2-associated GO terms across cancer lineages are Positive regulation of synapse structural plasticity, Response to molecule of fungal origin, and Cellular response to molecule of fungal origin. Each is linked with TNNI2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TNNI2-to-partner and partner-to-TNNI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of synapse structural plasticity grouped by TNNI2-low versus TNNI2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI2→partner) and Y-score (partner→TNNI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of synapse structural plasticity →	-1.365	-2.578	<.001	.001	3	8
OVARY	Response to molecule of fungal origin →	+0.977	+1.123	<.001	.006	3	8
OVARY	Cellular response to molecule of fungal origin →	+0.977	+1.123	<.001	.006	3	8
URINARY_TRACT	Response to indole-3-methanol →	+0.228	+2.251	<.001	<.001	3	7
URINARY_TRACT	Bundle of His cell to Purkinje myocyte communication →	+0.567	+3.050	.006	<.001	3	7
LUNG_NSCLC_LUSC	NMDA selective glutamate receptor signaling pathway →	+0.261	+0.670	.002	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,583 associations by consensus.

Positive regulation of synapse structural plasticity by TNNI2 expression — URINARY_TRACT

Explore this box plot interactively →