TNNI1

Across TCGA patient cohorts, TNNI1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,530 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNNI1-associated genes across cancer lineages are UTP6, PAXBP1, and PAQR3. Each is linked with TNNI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNI1-to-partner and partner-to-TNNI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNNI1 versus UTP6 in LUAD, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI1→partner) and Y-score (partner→TNNI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UTP6 →	-0.660	-0.944	.005	.002	3	2
LSCC	PAXBP1 →	-0.504	-0.362	<.001	.001	3	2
LUAD	PAQR3 →	-0.753	-0.751	.006	.003	3	2
LUAD	FABP12 →	-0.231	-0.822	.001	.002	3	2
LSCC	IGHV4-55 →	+1.666	+0.237	<.001	.003	3	2
LSCC	OR7E126P →	-0.780	-0.286	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,530 associations by consensus.

TNNI1 vs UTP6 — LUAD

Explore this scatter interactively →