TNNI1

Across TCGA cell cohorts, TNNI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,208 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNNI1-associated GO terms across cancer lineages are Regulation of CD8-positive, alpha-beta T cell extravasation, Desmosome assembly, and Cytotoxic T cell degranulation. Each is linked with TNNI1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TNNI1-to-partner and partner-to-TNNI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of CD8-positive, alpha-beta T cell extravasation grouped by TNNI1-low versus TNNI1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNI1→partner) and Y-score (partner→TNNI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of CD8-positive, alpha-beta T cell extravasation →	-0.207	-0.440	<.001	.001	3	8
STOMACH	Desmosome assembly →	+0.352	+0.504	.002	<.001	3	8
STOMACH	Cytotoxic T cell degranulation →	+0.234	+0.545	.002	.002	3	8
STOMACH	Positive regulation of adenylate cyclase activity →	-0.159	-0.614	<.001	.001	3	8
URINARY_TRACT	Keratinocyte development →	-0.481	-0.567	<.001	<.001	3	8
URINARY_TRACT	Chondroblast differentiation →	-1.645	-0.325	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,208 associations by consensus.

Regulation of CD8-positive, alpha-beta T cell extravasation by TNNI1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →