TNNC2

Across TCGA cell cohorts, TNNC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,895 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNNC2-associated GO terms across cancer lineages are Lipid droplet formation, Positive regulation of toll-like receptor signaling pathway, and Negative regulation of leukocyte apoptotic process. Each is linked with TNNC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TNNC2-to-partner and partner-to-TNNC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid droplet formation grouped by TNNC2-low versus TNNC2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNC2→partner) and Y-score (partner→TNNC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Lipid droplet formation →	+0.053	+0.733	.003	.004	3	6
BLOOD_Leukemia	Positive regulation of toll-like receptor signaling pathway →	+0.119	+0.315	<.001	.004	3	6
SKIN	Negative regulation of leukocyte apoptotic process →	+0.098	+0.257	.002	.003	3	5
KIDNEY	Response to unfolded protein →	+0.073	+0.292	.005	.003	2	6
BLOOD_Lymphoma	Negative regulation of protein deubiquitination →	+0.072	+0.200	.007	.003	3	5
BONE	Regulation of lymphocyte differentiation →	+0.048	+0.450	.002	.005	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,895 associations by consensus.

Lipid droplet formation by TNNC2 expression — LARGE_INTESTINE

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