TNMD

Across TCGA cell cohorts, TNMD RNA expression is significantly associated with the go_rna of many other GO terms, with 379 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNMD-associated GO terms across cancer lineages are Response to biphenyl, Vasculogenesis, and Regulation of isotype switching to IgE isotypes. Each is linked with TNMD in more than 3 cancer types. Because this analysis shows association rather than direction, both TNMD-to-partner and partner-to-TNMD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to biphenyl grouped by TNMD-low versus TNMD-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNMD→partner) and Y-score (partner→TNMD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Response to biphenyl →	+0.106	+0.032	.004	.007	2	4
LARGE_INTESTINE	Vasculogenesis →	-0.042	-0.433	.006	.006	3	3
LARGE_INTESTINE	Regulation of isotype switching to IgE isotypes →	-0.997	-0.506	<.001	.001	2	4
LARGE_INTESTINE	Positive regulation of isotype switching to IgE isotypes →	-0.997	-0.506	<.001	.001	2	4
LARGE_INTESTINE	Dentinogenesis →	-0.698	-0.536	.001	<.001	3	3
LARGE_INTESTINE	Response to gamma radiation →	-0.066	-0.790	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 379 associations by consensus.

Response to biphenyl by TNMD expression — CNS

Explore this box plot interactively →