TNMD

Across TCGA cell cohorts, TNMD total protein is significantly associated with the protein abundance of many other proteins, with 3,990 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TNMD-associated proteins across cancer lineages are PLPBP, ATP1A1, and SSB. Each is linked with TNMD in more than 11 cancer types. Because this analysis shows association rather than direction, both TNMD-to-partner and partner-to-TNMD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNMD versus PLPBP in OVARY, with a Pearson correlation of 0.46.

total protein associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNMD→partner) and Y-score (partner→TNMD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PLPBP →	+1.654	+0.902	.002	.005	3	12
STOMACH	ATP1A1 →	-1.428	-1.169	.001	.016	3	10
URINARY_TRACT	SSB →	+0.992	+0.697	.037	.014	3	10
OVARY	LSM1 →	+1.648	+0.752	<.001	.001	3	10
LUNG_SCLC	C19orf53 →	+0.885	+0.782	<.001	<.001	3	9
OVARY	MYG1 →	+1.567	+0.895	.010	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,990 associations by consensus.

TNMD vs PLPBP — OVARY

Explore this scatter interactively →