TNKS1BP1

Across TCGA patient cohorts, TNKS1BP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,329 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TNKS1BP1-associated genes across cancer lineages are CAPN2, SCML2, and IL1R1. Each is linked with TNKS1BP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TNKS1BP1-to-partner and partner-to-TNKS1BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNKS1BP1 versus CAPN2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNKS1BP1→partner) and Y-score (partner→TNKS1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAPN2 →	+0.781	+0.261	.002	<.001	3	7
LSCC	SCML2 →	-1.071	-0.261	<.001	<.001	3	6
GBM	IL1R1 →	+1.095	+0.331	.004	<.001	3	6
HNSC	NUP210 →	-1.071	-0.280	<.001	<.001	3	6
LUAD	RHOC →	+0.519	+0.251	<.001	<.001	3	6
HNSC	RAB39B →	-0.768	-0.381	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,329 associations by consensus.

TNKS1BP1 vs CAPN2 — BRCA

Explore this scatter interactively →