TNKS

Across TCGA patient cohorts, TNKS RNA expression is significantly associated with the protein abundance of many other proteins, with 15,421 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNKS-associated proteins across cancer lineages are CCAR2, XPO7, and ERI1. Each is linked with TNKS in more than 9 cancer types. Because this analysis shows association rather than direction, both TNKS-to-partner and partner-to-TNKS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNKS versus CCAR2 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNKS→partner) and Y-score (partner→TNKS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCAR2 →	+0.333	+1.001	<.001	<.001	3	10
BRCA	XPO7 →	+0.355	+0.605	<.001	<.001	3	8
OV	ERI1 →	+0.427	+0.899	<.001	<.001	3	7
BRCA	PCM1 →	+0.473	+0.576	<.001	<.001	3	7
OV	CCDC25 →	+0.330	+0.943	<.001	<.001	3	6
GBM	ZMYM2 →	+0.351	+0.556	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,421 associations by consensus.

TNKS vs CCAR2 — OV

Explore this scatter interactively →