TNK2

Across TCGA patient cohorts, TNK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,219 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNK2-associated proteins across cancer lineages are OPA1, PCYT1A, and SEPSECS. Each is linked with TNK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TNK2-to-partner and partner-to-TNK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNK2 versus OPA1 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNK2→partner) and Y-score (partner→TNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OPA1 →	+0.409	+0.541	<.001	<.001	3	4
LSCC	PCYT1A →	+0.639	+0.713	<.001	<.001	3	4
GBM	SEPSECS →	-0.286	-0.658	<.001	.001	3	4
LUAD	GOLM1 →	-0.502	-0.344	<.001	.006	3	4
LSCC	DNAJC1 →	-0.337	-0.453	<.001	<.001	3	4
LSCC	EEPD1_S173 →	+0.405	+0.517	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,219 associations by consensus.

TNK2 vs OPA1 — LSCC

Explore this scatter interactively →