TNK2

Across TCGA cell cohorts, TNK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,285 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNK2-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium or flagellum-dependent cell motility, and Glycerolipid biosynthetic process. Each is linked with TNK2 in more than 12 cancer types. Because this analysis shows association rather than direction, both TNK2-to-partner and partner-to-TNK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by TNK2-low versus TNK2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNK2→partner) and Y-score (partner→TNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.105	-0.968	<.001	.008	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.105	-0.968	<.001	.008	3	13
UPPER_AERODIGESTIVE_TRACT	Glycerolipid biosynthetic process →	+0.053	+1.454	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.042	+1.055	.002	.002	3	13
PANCREAS	Glycerophospholipid metabolic process →	+0.047	+1.210	<.001	<.001	3	13
BLOOD_Myeloma	Negative regulation of translational initiation →	+0.094	+0.844	.008	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,285 associations by consensus.

Cilium-dependent cell motility by TNK2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →