TNIP2

Across TCGA patient cohorts, TNIP2 mutation is significantly associated with the RNA expression of many other genes, with 1,755 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNIP2-associated genes across cancer lineages are RNA5SP411, RNA5SP412, and RNA5SP419. Each is linked with TNIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNIP2-to-partner and partner-to-TNIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by TNIP2-low versus TNIP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIP2→partner) and Y-score (partner→TNIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.232	+1.756	<.001	.005	3	2
UCEC	RNA5SP412 →	+0.624	+2.060	<.001	.002	3	2
UCEC	RNA5SP419 →	+0.881	+2.439	<.001	<.001	3	2
UCEC	RNA5SP410 →	+0.821	+2.410	<.001	<.001	3	2
UCEC	RNA5SP422 →	+0.883	+2.033	<.001	.001	3	2
UCEC	RNA5SP416 →	+0.717	+2.031	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,755 associations by consensus.

RNA5SP411 by TNIP2 expression — UCEC

Explore this box plot interactively →