TNIK

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNIK RNA expression is significantly associated with the protein abundance of many other proteins, with 18,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNIK-associated proteins across cancer lineages are TNIK_S548, TNIK_S678, and TNIK_S707. Each is linked with TNIK in more than 8 cancer types. Because this analysis shows association rather than direction, both TNIK-to-partner and partner-to-TNIK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNIK versus TNIK_S548 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIK→partner) and Y-score (partner→TNIK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTNIK_S548 →+1.258+1.163<.001<.00139
UCECTNIK_S678 →+1.204+1.297<.001<.00139
LSCCTNIK_S707 →+0.893+1.009<.001<.00139
UCECTNIK_S769 →+0.919+1.218<.001<.00139
PDACTNIK_S640 →+1.177+1.015<.001<.00137
LUADTNIK_S688 →+1.077+1.375<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,849 associations by consensus.

TNIK vs TNIK_S548 — OV

Per-sample scatter of TNIK vs TNIK_S548 in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration