TNFSF9

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFSF9 protein abundance is significantly associated with the RNA expression of many other genes, with 109 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFSF9-associated genes across cancer lineages are CLCN7, CPPED1, and AP3B2. Each is linked with TNFSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF9-to-partner and partner-to-TNFSF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF9 versus CLCN7 in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF9→partner) and Y-score (partner→TNFSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCLCN7 →+0.752+0.903<.001.00431
LSCCCPPED1 →+1.404+1.355.004<.00131
LSCCAP3B2 →+1.110+0.890.003.00531
LSCCCRX →+0.041+0.769.002.00831
LSCCTRIM32 →+0.596+0.876.008.00731
LSCCTRAFD1 →+0.773+0.903.003.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 109 associations by consensus.

TNFSF9 vs CLCN7 — LSCC

Per-sample scatter of TNFSF9 vs CLCN7 in LSCC (Pearson r = 0.69).

Explore this scatter interactively →

Exploration