TNFSF9

Across TCGA patient cohorts, TNFSF9 mutation is significantly associated with the RNA expression of many other genes, with 332 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF9-associated genes across cancer lineages are GGCTP2, CXCR5, and LSP1P3. Each is linked with TNFSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF9-to-partner and partner-to-TNFSF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGCTP2 grouped by TNFSF9-low versus TNFSF9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF9→partner) and Y-score (partner→TNFSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GGCTP2 →	+0.291	+5.271	<.001	.001	3	2
UCEC	CXCR5 →	+0.133	+3.931	.003	<.001	3	1
UCEC	LSP1P3 →	+0.376	+2.911	<.001	.001	3	1
UCEC	MEI1 →	+0.792	+3.343	<.001	.005	3	1
UCEC	DNAJC24 →	+0.486	+3.332	.005	.005	3	1
UCEC	CTU2 →	+0.504	+3.332	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 332 associations by consensus.

GGCTP2 by TNFSF9 expression — COAD

Explore this box plot interactively →